导航:生信文献复现

孟德尔随机化(MR):二甲双胍对原发性肝癌的保护作用及机制挖掘

论文《Mendelian Randomization and Bioinformatics Analysis Reveal the Potential Protective Role of Metformin in Primary Liver Cancer 》套路解析

双向MR+敏感性分析:挖掘血液代谢物与前列腺癌因果关系

论文《Associations between circulating metabolites and pca: a bidirectional two-sample Mendelian randomization study》套路解析

单细胞RNA-seq+机器学习+体外验证:三步搞定食管鳞癌诊断标志物筛选

文献《Integrative genomics unveils basement membrane-related diagnostic markers and therapeutic targets in esophageal squamous cell carcinoma | Biology Direct | Springer Nature Link》思路解析

单细胞WGCNA+LASSO-Cox:构建黑色素瘤预后模型

论文《Single cell sequencing analysis constructed the N7-methylguanosine (m7G)-related prognostic signature in uveal melanoma - PMC》套路解析

TCGA+多组学整合+免疫浸润:预测肺腺癌预后和免疫治疗反应

论文《Development and validation of polyamines metabolism-associated gene signatures to predict prognosis and immunotherapy response in lung adenocarcinoma》套路解析